To easily create a custom set you can go to JSON Against Humanity, select which packs you want and click 'Download plaintext'.
When you are ready simply paste everything in the file below the ---------- in the file into 'Blanks' section below and everything above the ---------- into the 'Fillers' section below and hit save
Optional: If you like you can remove duplicates from the file (there may be an overlap between the packs). Here is an online tool that can do this (just paste the whole text file in and click 'Remove Duplicates')